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Christian Gratzke Selected Research

Urethral Obstruction

1/2019Ghrelin Aggravates Prostate Enlargement in Rats with Testosterone-Induced Benign Prostatic Hyperplasia, Stromal Cell Proliferation, and Smooth Muscle Contraction in Human Prostate Tissues.
1/2019New strategies for inhibition of non-adrenergic prostate smooth muscle contraction by pharmacologic intervention.
10/2013Presence of phosphodiesterase type 5 in the spinal cord and its involvement in bladder outflow obstruction related bladder overactivity.
6/2013Spinal cord FAAH in normal micturition control and bladder overactivity in awake rats.
7/2012Effects on bladder function of combining elocalcitol and tolterodine in rats with outflow obstruction.
2/2011Cannabinor, a selective cannabinoid-2 receptor agonist, improves bladder emptying in rats with partial urethral obstruction.
8/2010Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction.
7/2010Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction.

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Christian Gratzke Research Topics

Disease

36Prostatic Neoplasms (Prostate Cancer)
04/2022 - 09/2014
24Lower Urinary Tract Symptoms
01/2022 - 07/2008
19Neoplasms (Cancer)
02/2022 - 07/2008
17Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
01/2022 - 06/2006
14Overactive Urinary Bladder (Overactive Bladder)
12/2019 - 06/2009
9Erectile Dysfunction
01/2022 - 11/2010
8Urethral Obstruction
01/2019 - 07/2010
6Carcinoma (Carcinomatosis)
04/2022 - 09/2010
6Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
05/2020 - 12/2007
5Neoplasm Metastasis (Metastasis)
01/2022 - 07/2017
4Urinary Bladder Neoplasms (Bladder Cancer)
08/2021 - 05/2011
4Urinary Retention
07/2019 - 01/2016
4Hyperplasia
04/2014 - 11/2008
3Kidney Calculi (Kidney Stone)
01/2022 - 07/2010
3Urinary Tract Infections (Urinary Tract Infection)
11/2021 - 06/2006
3Penile Neoplasms (Penile Cancer)
07/2021 - 11/2011
3Stress Urinary Incontinence
01/2020 - 12/2009
3Margins of Excision
10/2017 - 09/2011
3Pain (Aches)
07/2017 - 01/2016
2Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 08/2009
2Prostatitis
11/2021 - 02/2017
2Urinary Incontinence
12/2019 - 01/2016
2Lymphocele
01/2016 - 10/2012
2Wound Infection (Wound Infections)
01/2016 - 12/2009
2Inflammation (Inflammations)
10/2013 - 10/2012
2Carcinoma in Situ
11/2011 - 09/2010
2Pathologic Constriction (Stenosis)
04/2010 - 10/2009
1COVID-19
02/2022
1Urolithiasis
01/2022
1Urinary Calculi (Urinary Calculus)
01/2022
1Carcinogenesis
08/2021
1Lymphatic Metastasis
02/2021
1Ejaculatory Dysfunction
05/2020
1Staghorn Calculi
01/2020
1Urethral Stricture
01/2020
1Cysts
11/2019

Drug/Important Bio-Agent (IBA)

9AntigensIBA
01/2022 - 10/2016
7Prostate-Specific Antigen (Semenogelase)IBA
11/2021 - 06/2015
6gallium 68 PSMA-11IBA
11/2020 - 10/2016
5Muscarinic AntagonistsIBA
12/2019 - 07/2010
5Solifenacin SuccinateFDA Link
12/2019 - 06/2018
5mirabegronIBA
12/2019 - 06/2018
5Adrenergic Receptors (Adrenergic Receptor)IBA
01/2019 - 09/2011
4Tadalafil (Cialis)FDA Link
01/2022 - 09/2011
4Phosphodiesterase 5 InhibitorsIBA
11/2016 - 09/2011
4Type A Botulinum Toxins (Botox)FDA Link
07/2012 - 10/2008
3LigandsIBA
03/2021 - 11/2016
3Pharmaceutical PreparationsIBA
11/2017 - 02/2011
2Sildenafil Citrate (Viagra)FDA Link
01/2022 - 10/2013
2AndrogensIBA
01/2021 - 10/2013
2Type 5 Cyclic Nucleotide PhosphodiesterasesIBA
08/2018 - 10/2013
2CannabinoidsIBA
06/2013 - 02/2011
2Doxazosin (Cardura)FDA LinkGeneric
08/2010 - 07/2010
2fesoterodineFDA Link
08/2010 - 07/2010
2Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
08/2010 - 07/2010
25-hydroxymethyl tolterodineIBA
08/2010 - 07/2010
1isopropyl cyanoacrylateIBA
04/2022
1NivolumabIBA
01/2022
1Erlotinib Hydrochloride (CP 358,774)FDA Link
08/2021
1Epidermal Growth Factor (EGF)IBA
08/2021
1Immunotoxins (Immunotoxin)IBA
08/2021
1ErbB Receptors (EGF Receptor)IBA
08/2021
1Complement System Proteins (Complement)IBA
05/2021
1NAD (NADH)IBA
01/2021
1Thalidomide (Thalomid)FDA Link
01/2021
1Flavin-Adenine Dinucleotide (FAD)IBA
01/2021
1Choline (Choline Chloride)IBA
11/2020
1Biomarkers (Surrogate Marker)IBA
04/2020
1propiverineIBA
12/2019
1Polyglactin 910IBA
11/2019
1Testosterone (Sustanon)FDA Link
01/2019

Therapy/Procedure

27Therapeutics
04/2022 - 06/2006
24Prostatectomy (Retropubic Prostatectomy)
01/2022 - 04/2007
10Lymph Node Excision (Lymph Node Dissection)
01/2022 - 05/2011
8Radiotherapy
01/2022 - 03/2017
5Solid-State Lasers
04/2022 - 04/2007
5Transurethral Resection of Prostate (TURP)
01/2022 - 03/2009
4Lasers (Laser)
01/2022 - 03/2009
4Laser Therapy (Surgery, Laser)
01/2022 - 07/2009
3Drug Therapy (Chemotherapy)
01/2021 - 10/2013
3Catheters
07/2019 - 01/2016
3Cystectomy
04/2017 - 05/2011
3Semiconductor Lasers
03/2009 - 12/2007
2Suburethral Slings (Tension-Free Vaginal Tape)
01/2020 - 06/2010
2Transurethral Resection of Bladder
01/2020 - 01/2020
2Artificial Urinary Sphincter
01/2020 - 10/2009
2Lithotripsy (Extracorporeal Shockwave Lithotripsy)
07/2019 - 07/2010
2Castration
07/2017 - 01/2017
2Nephrectomy
09/2011 - 08/2009
1Eye Enucleation (Enucleation, Eye)
01/2022
1Morcellation
01/2022
1Brachytherapy
01/2022
1Extracorporeal Shockwave Therapy
01/2022
1Conservative Treatment
01/2021
1Precision Medicine
05/2020
1Kidney Transplantation
01/2020
1Nephrotomy
01/2020
1Stents
01/2020
1Sutures (Suture)
11/2019
1Surgical Instruments (Clip)
11/2019